The Ometepe airstrip in La Paloma, 1.5 km out of Moyogalpa, was inaugurated on May 29, 2014. The national carrier La Costeña Airlines operated flights to the island twice a week with small 12-seater aircrafts for affordable rates.

The flights to and from Ometepe connected to Nicaragua's capital Managua, to the port town of San Carlos at the South-Eastern end of Lake Nicaragua, and on to the Carribean side, to San Juan del Norte (Greytown) at the river mouth of the Rio San Juan.

Today however the flights are discontinued due to low demand.